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Grand Challenges Explorations (GCE) - Emerging Technologies for New Solutions in Global Health Priority Areas - Round 23

Grants to USA, Canada, and International Nonprofits, For-Profits, Agencies,
and IHEs to Apply New Technologies to Global Health Priorities

Agency Type:

Foundation / Corporation

Funding Source:

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Bill and Melinda Gates Foundation - Global Grand Challenges

Deadline Date:

04/10/19 11:30 AM Pacific Daylight Time


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Grants to USA, Canada, and International nonprofits, for-profit companies, agencies, and IHEs for the application of new technologies to help solve global health problems. Health priority areas include outcomes related to infectious diseases, child growth and development, pregnancy and birth, disease surveillance, and research into the development of new vaccines, drugs, and diagnostics. Funding is intended to foster and support impact in global health through innovative uses of emerging technologies.

Emerging technologies include – but are not limited to – artificial intelligence, materials science, wearable sensors, synthetic biology, nanotechnology, microscopy, augmented and virtual reality, geospatial mapping, robotics, and DNA sequencing. There is now an opportunity to build on these advances and explore new applications of these technologies – singly or in combination – to provide new ways of solving the key challenges in global health.

The highest priority will be given to approaches that:
- Represent potentially transformative approaches that would not have been funded by mechanisms focusing on individual technologies or subject areas
- Represent new perspectives on the problem being targeted, including applying insights from fields outside the priority global health areas that are the subject of this challenge
- Leverage existing data or biosamples from human cohorts or biorepositories of proven value.

The work proposed in an application must include a clear set of key experiments or activities that test the proposed idea in a way that could provide sufficient evidence to warrant funding. Proposals with vague descriptions or vague testing methodologies will not be funded.

All awardees will be permitted to contract for services, up to a maximum of $49,999 USD. This limit applies to funds paid by an awardee to any other organization (or an individual employed at another organization) as a subcontractor, including payments to co-PIs working at another organization. Awardees are entitled to purchase equipment, provided that the cost of each item is less than $5,000 USD. Phase I project funds may be used to cover the full direct costs of the project.

GrantWatch ID#:

GrantWatch ID#: 185423

Estimated Size of Grant:

- Awards of up to $100,000 USD are made in Phase I. Phase I awardees have one opportunity to apply for a follow-on Phase II award of up to $1,000,000 USD.

Term of Contract:

- Awarded projects start date is November 1, 2019.
- Phase I projects have a term of 18 months beginning on the project start date
- Phase II funding has a grant term of up to two years.

Additional Eligibility Criteria:

GCE is open to both foreign and domestic organizations, including non-profit organizations, for-profit companies, international organizations, government agencies, and academic institutions.

Government units or international executive order organizations confirm that: (a) You are an entity duly organized or formed, qualified to do business, and in good standing under the laws of the jurisdiction in which you are organized or formed; (b) You are not an individual (i.e., a natural person) or a disregarded entity (e.g., a sole proprietor or sole-owner entity) under U.S. law; (c) You have the right to enter into and fully perform this Agreement; and (d) Your performance will not violate any agreement or obligation between You and any third party. You will notify the Foundation immediately if any of this changes during the term of this Agreement.

For grantees in India FCRA Registration is required.

Foreign organizations may not use more than 20% of Grant Funds for activities in the U.S., including travel to or from the U.S. This limitation does not apply to Your subgrantees or subcontractors that: (a) are independent from and not controlled by You; (b) have provided You a proposal and budget describing how the funds will be used, and You have determined that the activities and costs are reasonable; and (c) are not Your agents.

No awardee will be entitled to use funds to cover indirect costs.

The Foundation will not consider funding approaches that:
- Are not aligned with the Gates foundation's priority areas and strategies
- Are not directly relevant to developing countries
- Lack a clearly articulated and testable hypothesis
- Lack a compelling plan for achieving proof of principle
- Lack a relevant indicator of success that can be demonstrated within the scope of the GCE Phase 1 award
- Represent incremental improvements to conventional solutions
- Represent basic research without clear relevance to the goals of this challenge
- Present unacceptable safety risks
- Detract from or interfere with beneficial practices.

Project funds may not be used to enroll human subjects in any research project subject to Institution Review Board (IRB) or Independent Ethics Committee (IEC) approval until such approval has been obtained for each site.

Pre-Application Information:

Proposals are due by Wednesday, April 10, 2019 11:30 a.m. U.S. Pacific Daylight Time.

Proposal review will be completed in June 2019, and notification of selections will be sent in October.

New users must create an account and submit proposals through the online portal. Applicants are encouraged to download the application form, which should be submitted either as a Microsoft Word or PDF document; no more than two pages in length.

The GCE initiative publishes topics and invites proposals two rounds a year. An applicant must submit under only one topic each round and may submit only one proposal. Submit your best idea. You may submit multiple ideas in partnership with collaborators, but an individual Principal Investigator may lead the submission of only one proposal each round. You may change your topic and edit your proposal any time before the application deadline.

Application instructions:

Selection process:


Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

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Please direct all questions by e-mail to:

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

USA Territories: American Samoa (USA)   Guam (USA)   Puerto Rico (USA)   Virgin Islands (USA)   Northern Mariana Islands (USA)

USA Compact Free Associations: The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)

Canada: Alberta   British Columbia   Manitoba   New Brunswick   Newfoundland and Labrador   Northwest Territories   Nova Scotia   Nunavut   Ontario   Prince Edward Island   Quebec   Saskatchewan   Yukon


International country outside of the USA, Israel and Canada.