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NIH Research Project Grant Program (R01)

Grants to USA, Canada, and International Nonprofits, For-Profits,
Agencies, and IHEs for Health-Related Research Projects

Agency Type:

Federal

Funding Source:

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National Institute of Health (NIH)

Deadline Date:

05/07/20 5:00 PM - Standard receipt date

Description:

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Grants to USA, Canada, and International nonprofit, for-profit, and faith-based organizations, government agencies, and IHEs to support a broad range of health-related research. Funding is intended to support a specific project that will be performed by the named investigator(s) in an area representing the investigator's particular interest and competencies, based on the mission of the NIH. All applications submitted to this Parent Funding Opportunity Announcement must propose clinical trial(s). Applications may be new, renewals, resubmissions, or revisions.

The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions. Applicants should note that some ICs only accept applications proposing mechanistic studies that meet NIH's definition of a clinical trial through this funding opportunity announcement.

NIH defines a clinical trial as, "A research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes."

NIH not only supports trials of safety and efficacy, it also supports mechanistic exploratory studies that meet the definition of a clinical trial and are designed to explore or understand a biological or behavioral process, the pathophysiology of a disease, or the mechanism of action of an intervention.  These studies may focus on basic and/or translational discovery research in healthy human subjects and in human subjects who are affected by the pathophysiology of diseases and disorders.  By addressing basic questions and concepts in biology, behavior, and pathophysiology, these studies may provide insight into understanding human diseases and disorders along with potential treatments or preventive strategies.  

NIH also supports biomarker studies that meet the definition of a clinical trial and that may provide information about physiological function, target engagement of novel therapeutics, and/or the impact of therapeutics on treatment response.  NIH thus supports studies that meet the definition of clinical trials (as noted above) but do not seek to establish safety, clinical efficacy, effectiveness, clinical management, and/or implementation of preventive, therapeutic, and services interventions.

GrantWatch ID#:

GrantWatch ID#: 158058

Number of Grants:

The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.

Term of Contract:

The scope of the proposed project should determine the project period. The maximum project period is 5 years.

Eligibility:

  • City or township governments
  • County governments
  • For profit organizations other than small businesses
  • Independent school districts
  • Indian housing authorities
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally funded tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities
  • See RFP and/or Grant Guidelines for full eligibility
  • Small businesses
  • Special district governments
  • State governments

Additional Eligibility Criteria:

Eligible Higher Education Institutions:
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education

The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)

Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)

For-Profit Organizations:
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)

Governments:
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)
- Eligible Agencies of the Federal Government
- U.S. Territory or Possession

Other:
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations
- Non-domestic (non-U.S.) Entities (Foreign Institutions)

Foreign Institutions
- Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
- Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.

Pre-Application Information:

Standard receipt dates for new grant applications are February 5, June 5, and October 5 and for renewal, resubmission, and revision grant applications are March 5, July 5, and November 5. AIDS and AIDS-related grant application due dates are May 7, September 7, and January 7.

There are several options available to submit your application through Grants.gov to NIH and Department of Health and Human Services partners. You must use one of these submission options to access the application forms for this opportunity:
- Use the NIH ASSIST system to prepare, submit and track your application online.
- Use an institutional system-to-system (S2S) solution to prepare and submit your application to Grants.gov and eRA Commons to track your application. Check with your institutional officials regarding availability.
- Use Grants.gov Workspace to prepare and submit your application and eRA Commons to track your application.

Applicants requesting $500,000 or more in direct costs in any year (excluding consortium F&A) must contact a Scientific/ Research Contact at least 6 weeks before submitting the application and follow the Policy on the Acceptance for Review of Unsolicited Applications that Request $500,000 or More in Direct Costs as described in the SF424 (R&R) Application Guide.

Required Registrations:
-Dun and Bradstreet Universal Numbering System (DUNS) - All registrations require that applicants be issued a DUNS number. After obtaining a DUNS number, applicants can begin both SAM and eRA Commons registrations. The same DUNS number must be used for all registrations, as well as on the grant application. For DUNS: http://fedgov.dnb.com/webform
-System for Award Management (SAM) (formerly CCR) – Applicants must complete and maintain an active registration, which requires renewal at least annually. The renewal process may require as much time as the initial registration. For SAM: https://www.sam.gov/portal/public/SAM/
-NATO Commercial and Government Entity (NCAGE) Code: Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM.
-eRA Commons: Organizations can register with the eRA Commons as they are working through their SAM or Grants.gov registration but all registrations must be in place by time of submission. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application.
-Grants.gov: Applicants must have an active DUNS number and SAM registration in order to complete the Grants.gov registration.

Program Directors/Principal Investigators (PD(s)/PI(s)):
All PD(s)/PI(s) must have an eRA Commons account. PD(s)/PI(s) should work with their organizational officials to either create a new account or to affiliate their existing account with the applicant organization in eRA Commons. If the PD/PI is also the organizational Signing Official, they must have two distinct eRA Commons accounts, one for each role. Obtaining an eRA Commons account can take up to 2 weeks.

Additional information: https://grants.nih.gov/grants/guide/pa-files/PA-19-055.html

FAQ:
https://grants.nih.gov/grants/ElectronicReceipt/faq_full.htm#application

Application guide: https://grants.nih.gov/grants/guide/url_redirect.htm?id=12000

Register for Grants.gov: https://www.grants.gov/web/grants/register.html

Grants.gov Workspace: https://www.grants.gov/web/grants/applicants/workspace-overview.html

View this opportunity on Grants.gov:
https://www.grants.gov/web/grants/view-opportunity.html?oppId=310141

For a list of application documents, see the Package tab (press Preview) on the Grants.gov page above.

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

ASSIST: https://public.era.nih.gov/assist/public/login.era?TARGET=https%3A%2F%2Fpublic.era.nih.gov%2Fassist%2F

eRA Commons: https://public.era.nih.gov/commons/public/login.do?TARGET=https%3A%2F%2Fpublic.era.nih.gov%2Fcommons%2FcommonsInit.do

Direct general questions to:
Email: GrantsInfo@nih.gov
Telephone: 301-945-7573

If you have difficulty accessing the full announcement electronically, please contact:
NIH OER Webmaster: FBOWebmaster@OD.NIH.GOV

Grants.gov Customer Support
Contact Center Telephone: 800-518-4726
Email: support@grants.gov

For a list of contacts, see: https://grants.nih.gov/grants/guide/contacts/parent_R01.html

CFDA Number:

93.113 -- Environmental Health / 93.172 -- Human Genome Research/93.173 -- Research Related to Deafness and Communication Disorders / 93.213 -- Research and Training in Complementary and Integrative Health / 93.233 -- National Center on Sleep Disorders Research / 93.273 -- Alcohol Research Programs / 93.279 -- Drug Abuse and Addiction Research Programs / 93.307 -- Minority Health and Health Disparities Research / 93.361 -- Nursing Research / 93.837 -- Cardiovascular Diseases Research / 93.838 -- Lung Diseases Research / 93.839 -- Blood Diseases and Resources Research / 93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders / 93.846 -- Arthritis, Musculoskeletal and Skin Diseases Research/ 93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders/93.855 -- Allergy and Infectious Diseases Research / 93.859 -- Biomedical Research and Research Training / 93.866 -- Aging Research/93.867 -- Vision Research

Funding or Pin Number:

PA-19-055

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

USA Territories: American Samoa (USA)   Guam (USA)   Puerto Rico (USA)   Virgin Islands (USA)   Northern Mariana Islands (USA)

USA Compact Free Associations: The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)

Canada: Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;

Israel

International country outside of the USA, Israel and Canada.

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